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Fig 1.

Inclusion flow chart.

Abbreviations: ADEM = acute demyelinating encephalomyelitis; MS = multiple sclerosis; NMO = neuromyelitis optica; PPMS = primary progressive MS; RRMS = relapsing-remitting MS

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Table 1.

Baseline clinical and demographic data and their correlation with EDSS outcome 10 years after disease onset

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Table 1 Expand

Table 2.

Variables of disease course and their correlation with EDSS outcome 10 years after disease onset

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Fig 2.

time to depression.

Kaplan-Meier curves of the risk of developing depression according to disability status 10 years after onset. Log rank test used for calculation of significancy.

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Fig 2 Expand

Fig 3.

time to cognitive dysfunction.

Kaplan-Meier curves of the risk of developing cognitive dysfunction according to disability status 10 years after onset. Log rank test used for calculation of significancy.

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Fig 3 Expand

Table 3.

Prognostic factors in RRMS according to EDSS outcome 10 years after disease onset.

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Table 3 Expand