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Fig 1.

PRISMA Flow Diagram of Search Results.

From: Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009). Peferred Reporting Iterns tor Systematic Reviews and Mela-Analyses: The PRISMA Statement. PLoS Med 6(6): e1000097. doi:10.1371/journal.pmed1000097 For more information, visit www.prisma-statement.org.

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Fig 2.

Risk of bias assessment; outcome: all-cause mortality.

Legend: Our assessment indicated low risk of bias for missing data in about 75% of trials. The level of blinding was adequate in only about 25% of the studies.

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Fig 3.

The network map of seven-node analysis; outcome: all-cause mortality.

Legend: Edges are weighted by precision.

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Fig 3 Expand

Table 1.

GRADE quality assessment of direct evidence of each pairwise treatment comparison for all-cause mortality.

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Table 1 Expand

Fig 4.

The predictive interval consistency plot from the consistency model of seven-node analysis; outcome: all-cause mortality without a reference standard.

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Fig 4 Expand

Table 2.

GRADE confidence assessments of indirect estimates per pairwise treatment comparison for all-cause mortality.

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Table 2 Expand

Table 3.

Direct, indirect, and NMA estimates of all-cause mortality with 95% confidence intervals and GRADE assessments for each pairwise comparison within the network of seven phosphate binders.

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Table 3 Expand