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Fig 1.

Signal detrending.

Detrending of a typical IBI record (left-hand panels) and a SBP record (right-hand panels) for the same patient during the same maneuver. Original data points and the line of global trend are plotted in upper panels, while the detrended fluctuations appear in bottom panels.

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Fig 1 Expand

Fig 2.

Histograms of detrended IBI time series for all subjects during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels).

Superposed histograms are shown for all control subjects (upper row), recently diagnosed DM patients (middle row), and long-standing DM patients (bottom row).

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Fig 2 Expand

Fig 3.

Histograms of detrended IBI time series for a typical control subject (upper row), a recently diagnosed DM patient (middle row), and a long-standing DM patient (bottom row), during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels).

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Fig 3 Expand

Fig 4.

Histograms of detrended SBP time series for all the subjects during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels).

Superposed histograms are shown for all control subjects (upper row), recently diagnosed DM patients (middle row), and long-standing DM patients (bottom row).

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Fig 4 Expand

Fig 5.

Histograms of detrended SBP time series for a typical control subject (upper row), a recently diagnosed DM patient (middle row), and a long-standing DM patient (bottom row), during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels).

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Fig 5 Expand

Fig 6.

Standard deviation of detrended IBI data for the different groups during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels).

The vertical crosshair corresponds to one standard deviation around the population average, while the horizontal one is the median.

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Fig 6 Expand

Fig 7.

Skewness with respect to the median for the different groups during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels), IBI (top row), and SBP (bottom row).

The vertical crosshair corresponds to one standard deviation around the population average, while the horizontal one is the median.

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Fig 7 Expand

Fig 8.

Kurtosis with respect to the median for the different groups during clinostatism (left-hand panels), orthostatism (middle panels), and controlled breathing (right-hand panels), IBI (top row) and SBP (bottom row).

The vertical crosshair corresponds to one standard deviation around the population average, while the horizontal one is the median.

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Fig 8 Expand

Table 1.

IBI’s statistical moments.

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Table 1 Expand

Table 2.

SBP’s statistical moments.

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Table 2 Expand

Fig 9.

The α parameter for the different groups during clinostatism (left-hand panel), orthostatism (middle panel), and controlled breathing (right-hand panel).

Crosshairs correspond to one standard deviation around the population average.

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Fig 9 Expand

Table 3.

α parameter.

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Table 3 Expand