Table 1.
ICD-9 Study Codes Utilized for TSS Case Ascertainment.
Table 2.
Surveillance Case Definition of TSS [28].
Figure 1.
Flow diagram of TSS case ascertainment.
From 2000–2003 TSS cases were identified from multiple data sources including ICD-9 hospital discharge codes, cases reported to the Minnesota Unexplained Critical Illness and Death of Possible Infectious Etiology project (UNEX), and death certificate data using ICD-10 code A48.3. From 2004–2006 TSS cases were identified from only the TSS-specific ICD-9 hospital discharge code.
Table 3.
Description of Toxic Shock Syndrome Cases.
Table 4.
Comparison of Susceptibility Patterns and Superantigens among Isolates Associated with Menstrual and Non-menstrual Toxic Shock Syndrome Cases.
Table 5.
Average Annual Toxic Shock Syndrome Incidence by Age and Gender Groups During the Period of Most Complete Case Ascertainment, 2000–2003.
Figure 2.
Annual incidence of menstrual and non-menstrual TSS across years 2000–2006.
Annual incidence of TSS across years 2000–2006 of menstrual (A) and non-menstrual (B) TSS stratified by age ≤24 and >24 years using only cases receiving the TSS specific ICD-9 code. Error bars represent 95% confidence limits. Frequentist Poisson regressions were used to calculate P-values for test of trend. Over years 2000–2006 among menstrual TSS aged ≤24 years test of trend was not significant (p = 0.22) as was non-menstrual age ≤24 years (p = 0.69) and >24 years (p = 0.40) There was a significant decreasing annual incidence over 2000–2006 in menstrual TSS aged >24 years (test of trend p = 0.02).