High-intensity irreversible electroporation targeting intracellular structures enhance tumor ablation in lung cancer models
Fig 7
in vitro ultrastructural analysis via transmission electron microscopy.
(1 & 2) Control cells showed intact plasma membranes, nuclear membranes, and mitochondria. (3 & 4) HEF caused severe plasma membrane rupture, substantial nuclear membrane inflation, and extensive mitochondrial damage. (5 & 6) LEF induced moderate plasma membrane disruption, mild nuclear membrane stress, and partial mitochondrial damage. Arrows indicate structures: (→) plasma membrane, (→) nuclear membrane, and (>) mitochondria. Scale bars represent magnification as indicated.