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High-intensity irreversible electroporation targeting intracellular structures enhance tumor ablation in lung cancer models

Fig 3

The electrophysiological responses of A549 cells.

(1) Change in electrical resistance (Ω) in response to different electric field strengths. (2) Cytomembrane potential (CMP). (3) Cytosolic calcium concentration. Data is represented as mean ± SEM (n = 3). Multiple-group comparisons were analyzed using one-way ANOVA followed by Tukey’s HSD post hoc test, with statistical significance indicated as: ###p < 0.001; N.S, not significant. Two-group tests were analyzed using unpaired two-tailed t-tests, with significance indicated as: *p < 0.05, **p < 0.01, ***p < 0.001.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0346472.g003