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Open Access
Peer-reviewed
Research Article
Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS
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Jan Philipp Radtke ,
Contributed equally to this work with: Jan Philipp Radtke, Francesco Giganti
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft
* E-mail: j.radtke@dkfz-heidelberg.de
Current address: Department of Urology, University Hospital Essen, Essen, Germany
¶‡ These authors are first authors on this work.
Affiliations Department of Urology, University Hospital Heidelberg, Heidelberg, Germany, Department of Radiology, German Cancer Research Center, Heidelberg, Germany
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Francesco Giganti ,
Contributed equally to this work with: Jan Philipp Radtke, Francesco Giganti
Roles Data curation, Formal analysis, Investigation, Writing – original draft
¶‡ These authors are first authors on this work.
Affiliations Department of Radiology, University College London Hospital NHS Foundation Trust, London, United Kingdom, Division of Surgery & Interventional Science, University College London, London, United Kingdom
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Manuel Wiesenfarth,
Roles Formal analysis, Methodology, Software, Supervision, Validation, Writing – review & editing
Affiliation Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany
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Armando Stabile,
Roles Formal analysis, Project administration, Writing – original draft
Affiliations Division of Surgery & Interventional Science, University College London, London, United Kingdom, Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, Division of Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, Vita-Salute San Raffaele University, Milan, Italy
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Jose Marenco,
Roles Investigation
Affiliation Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Clement Orczyk,
Roles Formal analysis, Investigation
Affiliations Division of Surgery & Interventional Science, University College London, London, United Kingdom, Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Veeru Kasivisvanathan,
Roles Validation, Writing – original draft
Affiliations Division of Surgery & Interventional Science, University College London, London, United Kingdom, Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Joanne Nyaboe Nyarangi-Dix,
Roles Investigation
Affiliation Department of Urology, University Hospital Heidelberg, Heidelberg, Germany
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Viktoria Schütz,
Roles Investigation
Affiliation Department of Urology, University Hospital Heidelberg, Heidelberg, Germany
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Svenja Dieffenbacher,
Roles Formal analysis, Investigation
Affiliations Department of Urology, University Hospital Heidelberg, Heidelberg, Germany, Department of Radiology, German Cancer Research Center, Heidelberg, Germany
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Magdalena Görtz,
Roles Data curation, Formal analysis
Affiliation Department of Urology, University Hospital Heidelberg, Heidelberg, Germany
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Albrecht Stenzinger,
Roles Data curation, Investigation, Validation
Affiliation Institute of Pathology, University of Heidelberg, Heidelberg Germany
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Wilfried Roth,
Roles Investigation, Resources
Affiliations Institute of Pathology, University of Heidelberg, Heidelberg Germany, Institute of Pathology, University Medicine Mainz, Mainz, Germany
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Alex Freeman,
Roles Data curation, Investigation, Validation
Affiliation Department of Pathology, University College Hospital, London, United Kingdom
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Shonit Punwani,
Roles Data curation, Investigation, Resources
Affiliations Department of Radiology, University College London Hospital NHS Foundation Trust, London, United Kingdom, Centre for Medical Imaging, University College London Hospitals NHS Foundation Trust, University College London, London, United Kingdom
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David Bonekamp,
Roles Data curation, Investigation, Supervision, Validation, Writing – original draft
Affiliation Department of Radiology, German Cancer Research Center, Heidelberg, Germany
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Heinz-Peter Schlemmer,
Roles Formal analysis, Writing – original draft
Affiliation Department of Radiology, German Cancer Research Center, Heidelberg, Germany
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Markus Hohenfellner,
Roles Supervision
Affiliation Department of Urology, University Hospital Heidelberg, Heidelberg, Germany
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Mark Emberton,
Roles Methodology, Supervision, Validation, Writing – original draft
Affiliations Division of Surgery & Interventional Science, University College London, London, United Kingdom, Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Caroline M. Moore
Roles Conceptualization, Methodology, Project administration, Supervision, Writing – original draft
Affiliations Division of Surgery & Interventional Science, University College London, London, United Kingdom, Department of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS
- Jan Philipp Radtke,
- Francesco Giganti,
- Manuel Wiesenfarth,
- Armando Stabile,
- Jose Marenco,
- Clement Orczyk,
- Veeru Kasivisvanathan,
- Joanne Nyaboe Nyarangi-Dix,
- Viktoria Schütz,
- Svenja Dieffenbacher
- Published: August 26, 2019
- https://doi.org/10.1371/journal.pone.0221350