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The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis
- Carl L. Manthey ,
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Beverley A. Moore ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
* E-mail: bamoore1786@gmail.com
Current address: BA Moore Pharmaceutical Consulting, LLC, Collegeville, Pennsylvania, United States of America
¶‡ These authors are joint senior authors on this work.
Affiliation Janssen Research & Development, LLC, Pennsylvania, United States of America
⨯ - Yanqing Chen,
- Matthew J. Loza,
- Xiang Yao,
- Hao Liu,
- Stanley M. Belkowski,
- Holly Raymond-Parks,
- Paul J. Dunford,
- Francisco Leon,
- Jennifer E. Towne,
- Scott E. Plevy
http://orcid.org/0000-0001-6355-8608
The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis
- Carl L. Manthey,
- Beverley A. Moore,
- Yanqing Chen,
- Matthew J. Loza,
- Xiang Yao,
- Hao Liu,
- Stanley M. Belkowski,
- Holly Raymond-Parks,
- Paul J. Dunford,
- Francisco Leon
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- Published: November 11, 2019
- https://doi.org/10.1371/journal.pone.0223918