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Open Access
Peer-reviewed
Research Article
Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases
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Matthew Traylor,
Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Clinical Neurosciences, Stroke Research Group, University of Cambridge, Cambridge, United Kingdom, Department of Medical and Molecular Genetics, King’s College London, London, United Kingdom
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Rachel Knevel,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Brigham and Women’s Hospital, Division of Genetics, Raychaudhuri Lab, Boston, MA, United States of America, Broad institute, Cambridge, MA, United States of America, Department of Rheumatology C1-R, Leiden University Medical Center, Albinusdreef, Leiden, the Netherlands
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Jing Cui,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Division of Rheumatology Immunology and Allergy Brigham & Women's Hospital Harvard Medical School Boston, MA, United States of America
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John Taylor,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Leeds Institute of Cancer & Pathology, Worsley Building Level 11 (LIDA), Clarendon Way, Leeds, United Kingdom
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Westra Harm-Jan,
Roles Formal analysis
Affiliations Brigham and Women’s Hospital, Division of Genetics, Raychaudhuri Lab, Boston, MA, United States of America, Broad institute, Cambridge, MA, United States of America
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Philip G. Conaghan,
Roles Data curation, Writing – review & editing
Affiliations Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
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Andrew P. Cope,
Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing
Affiliation Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, King's College London, London, United Kingdom
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Charles Curtis,
Roles Data curation, Writing – review & editing
Affiliations NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London, London, United Kingdom, SGDP Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
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Paul Emery,
Roles Data curation, Writing – review & editing
Affiliations Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
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Stephen Newhouse,
Roles Data curation, Writing – review & editing
Affiliations NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London, London, United Kingdom, Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, London, United Kingdom
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Hamel Patel,
Roles Data curation, Writing – review & editing
Affiliation NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London, London, United Kingdom
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Sophia Steer,
Roles Conceptualization, Data curation, Writing – review & editing
Affiliation Department of Rheumatology, King’s College Hospital, Denmark Hill, London, United Kingdom
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Peter Gregersen,
Roles Data curation, Writing – review & editing
Affiliation The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, United States of America
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Nancy A. Shadick,
Roles Data curation, Writing – review & editing
Affiliation Division of Rheumatology Immunology and Allergy Brigham & Women's Hospital Harvard Medical School Boston, MA, United States of America
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Michael E. Weinblatt,
Roles Data curation, Writing – review & editing
Affiliation Division of Rheumatology Immunology and Allergy Brigham & Women's Hospital Harvard Medical School Boston, MA, United States of America
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Annette Van Der Helm-van Mil,
Roles Data curation, Writing – review & editing
Affiliation Department of Rheumatology C1-R, Leiden University Medical Center, Albinusdreef, Leiden, the Netherlands
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Jennifer H. Barrett,
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, School of Medicine, University of Leeds, Leeds, United Kingdom
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Ann W. Morgan,
Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
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Cathryn M. Lewis,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Medical and Molecular Genetics, King’s College London, London, United Kingdom, SGDP Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
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Ian C. Scott
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: i.scott@keele.ac.uk
Affiliations Primary Care Centre Versus Arthritis, Research Institute for Primary Care and Health Sciences, Primary Care Sciences, Keele University, Keele, United Kingdom, Haywood Academic Rheumatology Centre, Haywood Hospital, Midlands Partnership NHS Foundation Trust, High Lane, Burslem, Staffordshire, United Kingdom
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Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases
- Matthew Traylor,
- Rachel Knevel,
- Jing Cui,
- John Taylor,
- Westra Harm-Jan,
- Philip G. Conaghan,
- Andrew P. Cope,
- Charles Curtis,
- Paul Emery,
- Stephen Newhouse
- Published: October 9, 2019
- https://doi.org/10.1371/journal.pone.0223246