Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions

• Gregory S. Honda,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

  Affiliations National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America, Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America

  http://orcid.org/0000-0001-7713-9850

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• Robert G. Pearce,

  Roles Software, Writing – review & editing

  Affiliations National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America, Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America

  http://orcid.org/0000-0003-3168-4049

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• Ly L. Pham,

  Roles Methodology, Writing – review & editing

  Affiliations National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America, Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America

  http://orcid.org/0000-0001-8467-2645

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• R. W. Setzer,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America

  http://orcid.org/0000-0002-6709-9186

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• Barbara A. Wetmore,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation National Exposure Research Laboratory, U.S. EPA, Research Triangle Park, North Carolina, United States of America

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• Nisha S. Sipes,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Division of the National Toxicology Program, NIEHS, Research Triangle Park, North Carolina, United States of America

  http://orcid.org/0000-0003-4203-6426

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• Jon Gilbert,

  Roles Data curation, Investigation

  Affiliation Cyprotex, Watertown, MA, United States of America

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• Briana Franz,

  Roles Data curation, Investigation

  Affiliation Cyprotex, Watertown, MA, United States of America

  http://orcid.org/0000-0002-9513-8234

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• Russell S. Thomas,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America

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• John F. Wambaugh

  Roles Conceptualization, Data curation, Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: wambaugh.john@epa.gov

  Affiliation National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America

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