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Open Access

Peer-reviewed

Research Article

Assessment of PD-L1 mRNA and protein expression in non-small cell lung cancer, head and neck squamous cell carcinoma and urothelial carcinoma tissue specimens using RNAScope and immunohistochemistry

David Jonathan Duncan ,

Roles Data curation, Investigation, Project administration, Resources, Validation, Writing – original draft

* E-mail: david.duncan@astrazeneca.com

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom

http://orcid.org/0000-0001-6661-576X

⨯
Marietta Scott,

Roles Conceptualization, Data curation, Formal analysis, Software, Validation, Visualization, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom
⨯
Paul Scorer,

Roles Investigation, Project administration, Resources, Validation, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom
⨯
Craig Barker

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom
⨯

Assessment of PD-L1 mRNA and protein expression in non-small cell lung cancer, head and neck squamous cell carcinoma and urothelial carcinoma tissue specimens using RNAScope and immunohistochemistry

David Jonathan Duncan,
Marietta Scott,
Paul Scorer,
Craig Barker

x

Published: April 15, 2019
https://doi.org/10.1371/journal.pone.0215393

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Cell staining
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Non-small cell lung cancer
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Cancers and neoplasms
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Immunohistochemistry techniques
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Immune cells
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Head and neck cancers
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Head and neck squamous cell carcinoma
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Protein expression
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