About the Authors

David Jonathan Duncan

Roles Data curation, Investigation, Project administration, Resources, Validation, Writing – original draft

david.duncan@astrazeneca.com

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom

Marietta Scott

Roles Conceptualization, Data curation, Formal analysis, Software, Validation, Visualization, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom

Paul Scorer

Roles Investigation, Project administration, Resources, Validation, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom

Craig Barker

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Precision Medicine Laboratories, Precision Medicine and Genomics, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom

Competing Interests

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: DJD, MS, PS, and CB are paid employees and shareholders of AstraZeneca. This does not alter their adherence to PLOS ONE policies on sharing data and materials. There are no patents, products in development, or marketed products to declare here.