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Open Access
Peer-reviewed
Research Article
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells
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Jennifer E. Chung ,
Contributed equally to this work with: Jennifer E. Chung, Wendy Magis
Roles Formal analysis, Investigation, Writing ā€“ original draft
Affiliation Innovative Genomics Institute, University of California, Berkeley, CA, United States of America
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Wendy Magis ,
Contributed equally to this work with: Jennifer E. Chung, Wendy Magis
Roles Formal analysis, Investigation
Affiliation Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America
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Jonathan Vu,
Roles Investigation, Methodology
Affiliation Innovative Genomics Institute, University of California, Berkeley, CA, United States of America
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Seok-Jin Heo,
Roles Formal analysis, Investigation, Methodology, Resources
Affiliation Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America
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Kirmo Wartiovaara,
Roles Conceptualization
Affiliations Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America, Research Programs Unit, Molecular Neurology and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Clinical Genetics, HUSLAB, Helsinki University Central Hospital, Helsinki, Finland
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Mark C. Walters,
Roles Conceptualization, Writing ā€“ review & editing
Affiliations Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America, Blood and Marrow Transplant Program, Division of Hematology, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America
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Ryo Kurita,
Roles Resources
Affiliation Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan
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Yukio Nakamura,
Roles Resources
Affiliations Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
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Dario Boffelli,
Roles Data curation, Formal analysis, Project administration, Writing ā€“ review & editing
Affiliation Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America
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David I. K. Martin ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing ā€“ original draft, Writing ā€“ review & editing
* E-mail: dewittm@berkeley.edu (MAD); jcorn@berkeley.edu (JEC); dimartin@chori.org (DIKM)
Affiliation Childrenā€™s Hospital Oakland Research Institute, UCSF Benioff Childrenā€™s Hospital, Oakland, CA, United States of America
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Jacob E. Corn ,
Roles Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing ā€“ review & editing
* E-mail: dewittm@berkeley.edu (MAD); jcorn@berkeley.edu (JEC); dimartin@chori.org (DIKM)
Affiliations Innovative Genomics Institute, University of California, Berkeley, CA, United States of America, Department of Molecular and Cellular Biology, University of California, Berkeley, CA, United States of America
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Mark A. DeWitt
Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing ā€“ original draft, Writing ā€“ review & editing
* E-mail: dewittm@berkeley.edu (MAD); jcorn@berkeley.edu (JEC); dimartin@chori.org (DIKM)
Affiliation Innovative Genomics Institute, University of California, Berkeley, CA, United States of America
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CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells
- Jennifer E. Chung,
- Wendy Magis,
- Jonathan Vu,
- Seok-Jin Heo,
- Kirmo Wartiovaara,
- Mark C. Walters,
- Ryo Kurita,
- Yukio Nakamura,
- Dario Boffelli,
- David I. K. Martin
- Published: January 15, 2019
- https://doi.org/10.1371/journal.pone.0208237