Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

Sajid Javed; Leanne Marsay; Alice Wareham; Kuiama S. Lewandowski; Ann Williams; Michael J. Dennis; Sally Sharpe; Richard Vipond; Nigel Silman; Graham Ball; Karen E. Kempsell

doi:10.1371/journal.pone.0154320

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Peer-reviewed

Research Article

Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

Sajid Javed ,

Contributed equally to this work with: Sajid Javed, Leanne Marsay, Karen E. Kempsell

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Leanne Marsay ,

Contributed equally to this work with: Sajid Javed, Leanne Marsay, Karen E. Kempsell

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Alice Wareham,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Kuiama S. Lewandowski,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Ann Williams,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Michael J. Dennis,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Sally Sharpe,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Richard Vipond,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Nigel Silman,

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯
Graham Ball,

Affiliation School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham, United Kingdom
⨯
Karen E. Kempsell

Contributed equally to this work with: Sajid Javed, Leanne Marsay, Karen E. Kempsell

* E-mail: karen.kempsell@phe.gov.uk

Affiliation Public Health England, Infection Services, Health Protection Agency Porton, Porton Down, Salisbury, Wiltshire, United Kingdom
⨯

Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

Sajid Javed,
Leanne Marsay,
Alice Wareham,
Kuiama S. Lewandowski,
Ann Williams,
Michael J. Dennis,
Sally Sharpe,
Richard Vipond,
Nigel Silman,
Graham Ball

Published: May 26, 2016
https://doi.org/10.1371/journal.pone.0154320

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