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Correction: Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

  • Sajid Javed,
  • Leanne Marsay,
  • Alice Wareham,
  • Kuiama S. Lewandowski,
  • Ann Williams,
  • Michael J. Dennis,
  • Sally Sharpe,
  • Richard Vipond,
  • Nigel Silman,
  • Graham Ball,
  • Karen E. Kempsell

Correction: Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

  • Sajid Javed, 
  • Leanne Marsay, 
  • Alice Wareham, 
  • Kuiama S. Lewandowski, 
  • Ann Williams, 
  • Michael J. Dennis, 
  • Sally Sharpe, 
  • Richard Vipond, 
  • Nigel Silman, 
  • Graham Ball
PLOS
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The text in Fig 1 highlighting rows of expression data by week is incorrectly reversed. The authors have provided a corrected version here.

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Fig 1. Cluster analysis of temporally expressed entities in peripheral blood leukocytes of Cynomolgus Macaques (all animals) pre-(week 0) or post (weeks 1–6) aerosol-challenge with M. tuberculosis.

These exhibit patterns of up- (cluster 2) or down-regulation (cluster 1) across the six week time course of the experiment. Cluster 2b1 (highlighted) contains co-expressed entities, FOS, IL8 and KLF2.

https://doi.org/10.1371/journal.pone.0159783.g001

Reference

  1. 1. Javed S, Marsay L, Wareham A, Lewandowski KS, Williams A, Dennis MJ, et al. (2016) Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification. PLoS ONE 11(5): e0154320. pmid:27228113