RAD51B in Familial Breast Cancer

• Liisa M. Pelttari,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Sofia Khan,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Mikko Vuorela,

  Affiliation Laboratory of Cancer Genetics and Tumor Biology, Cancer Research and Translational Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland

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• Johanna I. Kiiski,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Sara Vilske,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Viivi Nevanlinna,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Salla Ranta,

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Johanna Schleutker,

  Affiliations BioMediTech, University of Tampere, Tampere, Finland, Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland, Tyks Microbiology and Genetics, Department of Medical Genetics, Turku University Hospital, Turku, Finland

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• Robert Winqvist,

  Affiliations Laboratory of Cancer Genetics and Tumor Biology, Cancer Research and Translational Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland, Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland

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• Anne Kallioniemi,

  Affiliations BioMediTech, University of Tampere, Tampere, Finland, Fimlab Laboratories, Tampere, Finland

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• Thilo Dörk,

  Affiliation Gynaecology Research Unit, Hannover Medical School, Hannover, Germany

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• Natalia V. Bogdanova,

  Affiliation Radiation Oncology Research Unit, Hannover Medical School, Hannover, Germany

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• Jonine Figueroa,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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• Paul D. P. Pharoah,

  Affiliations Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Marjanka K. Schmidt,

  Affiliation Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands

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• Alison M. Dunning,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom

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• Montserrat García-Closas,

  Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America, Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom

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• Manjeet K. Bolla,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Joe Dennis,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Kyriaki Michailidou,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Qin Wang,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• John L. Hopper,

  Affiliation Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, Australia

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• Melissa C. Southey,

  Affiliation Department of Pathology, The University of Melbourne, Melbourne, Australia

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• Efraim H. Rosenberg,

  Affiliation Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands

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• Peter A. Fasching,

  Affiliations Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, University of California Los Angeles, Los Angeles, California, United States of America

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• Matthias W. Beckmann,

  Affiliation Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany

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• Julian Peto,

  Affiliation Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Isabel dos-Santos-Silva,

  Affiliation Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Elinor J. Sawyer,

  Affiliation Research Oncology, Guy’s Hospital, King's College London, London, United Kingdom

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• Ian Tomlinson,

  Affiliation Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom

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• Barbara Burwinkel,

  Affiliations Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany, Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Harald Surowy,

  Affiliations Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany, Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Pascal Guénel,

  Affiliations Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France, University Paris-Sud, Villejuif, France

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• Thérèse Truong,

  Affiliations Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France, University Paris-Sud, Villejuif, France

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• Stig E. Bojesen,

  Affiliations Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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• Børge G. Nordestgaard,

  Affiliations Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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• Javier Benitez,

  Affiliations Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain, Centro de Investigación en Red de Enfermedades Raras, Valencia, Spain

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• Anna González-Neira,

  Affiliation Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain

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• Susan L. Neuhausen,

  Affiliation Beckman Research Institute of City of Hope, Duarte, California, United States of America

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• Hoda Anton-Culver,

  Affiliation Department of Epidemiology, University of California Irvine, Irvine, California, United States of America

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• Hermann Brenner,

  Affiliations Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany, Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany

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• Volker Arndt,

  Affiliation Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Alfons Meindl,

  Affiliation Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany

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• Rita K. Schmutzler,

  Affiliations Center for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany

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• Hiltrud Brauch,

  Affiliations German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany

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• Thomas Brüning,

  Affiliation Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany

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• Annika Lindblom,

  Affiliation Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

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• Sara Margolin,

  Affiliation Department of Oncology—Pathology, Karolinska Institutet, Stockholm, Sweden

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• Arto Mannermaa,

  Affiliations Cancer Center, Kuopio University Hospital, Kuopio, Finland, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland, Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland

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• Jaana M. Hartikainen,

  Affiliations Cancer Center, Kuopio University Hospital, Kuopio, Finland, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland, Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland

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• Georgia Chenevix-Trench,

  Affiliation Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia

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• kConFab/AOCS Investigators ,

  ¶Membership of the kConFab/AOCS Investigators is listed in the Acknowledgments.

  Affiliations Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia, Peter MacCallum Cancer Center, The University of Melbourne, Melbourne, Australia

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• Laurien Van Dyck,

  Affiliations Vesalius Research Center, VIB, Leuven, Belgium, Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium

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• Hilde Janssen,

  Affiliation Leuven Multidisciplinary Breast Center, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium

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• Jenny Chang-Claude,

  Affiliations Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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• Anja Rudolph,

  Affiliation Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Paolo Radice,

  Affiliation Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy

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• Paolo Peterlongo,

  Affiliation IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy

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• Emily Hallberg,

  Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

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• Janet E. Olson,

  Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

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• Graham G. Giles,

  Affiliations Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, Australia, Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia

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• Roger L. Milne,

  Affiliations Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, Australia, Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia

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• Christopher A. Haiman,

  Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Fredrick Schumacher,

  Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

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• Jacques Simard,

  Affiliation Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada

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• Martine Dumont,

  Affiliation Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada

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• Vessela Kristensen,

  Affiliations Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway

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• Anne-Lise Borresen-Dale,

  Affiliations Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

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• Wei Zheng,

  Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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• Alicia Beeghly-Fadiel,

  Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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• Mervi Grip,

  Affiliation Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland

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• Irene L. Andrulis,

  Affiliations Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

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• Gord Glendon,

  Affiliation Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada

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• Peter Devilee,

  Affiliations Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands

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• Caroline Seynaeve,

  Affiliation Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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• Maartje J. Hooning,

  Affiliation Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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• Margriet Collée,

  Affiliation Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

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• Angela Cox,

  Affiliation Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, United Kingdom

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• Simon S. Cross,

  Affiliation Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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• Mitul Shah,

  Affiliation Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom

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• Robert N. Luben,

  Affiliation Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Ute Hamann,

  Affiliation Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Diana Torres,

  Affiliations Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany, Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia

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• Anna Jakubowska,

  Affiliation Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland

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• Jan Lubinski,

  Affiliation Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland

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• Fergus J. Couch,

  Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

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• Drakoulis Yannoukakos,

  Affiliation Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research "Demokritos", Athens, Greece

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• Nick Orr,

  Affiliation Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom

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• Anthony Swerdlow,

  Affiliations Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom, Division of Breast Cancer Research, The Institute of Cancer Research, London, United Kingdom

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• Hatef Darabi,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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• Jingmei Li,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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• Kamila Czene,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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• Per Hall,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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• Douglas F. Easton,

  Affiliations Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Johanna Mattson,

  Affiliation Department of Oncology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Carl Blomqvist,

  Affiliation Department of Oncology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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• Kristiina Aittomäki,

  Affiliation Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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•  [ ... ],
• Heli Nevanlinna

  * E-mail: heli.nevanlinna@hus.fi

  Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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