Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function

Fernando Aprile-Garcia; Michael W. Metzger; Marcelo Paez-Pereda; Herbert Stadler; Matías Acuña; Ana C. Liberman; Sergio A. Senin; Juan Gerez; Esteban Hoijman; Damian Refojo; Mišo Mitkovski; Markus Panhuysen; Walter Stühmer; Florian Holsboer; Jan M. Deussing; Eduardo Arzt

doi:10.1371/journal.pone.0151862

Loading metrics

Open Access

Peer-reviewed

Research Article

Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function

Fernando Aprile-Garcia,

Affiliations Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina, Departamento de Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Michael W. Metzger,

Affiliation Max Planck Institute of Psychiatry, 80804, Munich, Germany
⨯
Marcelo Paez-Pereda,

Affiliation Max Planck Institute of Psychiatry, 80804, Munich, Germany
⨯
Herbert Stadler,

Affiliation Affectis Pharmaceuticals, 44227, Dortmund, Germany
⨯
Matías Acuña,

Affiliation Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina
⨯
Ana C. Liberman,

Affiliation Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina
⨯
Sergio A. Senin,

Affiliation Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina
⨯
Juan Gerez,

Affiliation Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina
⨯
Esteban Hoijman,

Affiliation Centro de Microscopías Avanzadas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Damian Refojo,

Affiliation Max Planck Institute of Psychiatry, 80804, Munich, Germany
⨯
Mišo Mitkovski,

Affiliation Max Planck Institute of Experimental Medicine, 37075, Göttingen, Germany
⨯
Markus Panhuysen,

Affiliation Affectis Pharmaceuticals, 44227, Dortmund, Germany
⨯
Walter Stühmer,

Affiliation Max Planck Institute of Experimental Medicine, 37075, Göttingen, Germany
⨯
Florian Holsboer,

Affiliations Max Planck Institute of Psychiatry, 80804, Munich, Germany, HMNC Brain Health, Munich, Germany
⨯
Jan M. Deussing,

Affiliation Max Planck Institute of Psychiatry, 80804, Munich, Germany
⨯
[ ... ],
Eduardo Arzt

* E-mail: earzt@ibioba-mpsp-conicet.gov.ar

Affiliations Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET- Partner Institute of the Max Planck Society, Buenos Aires, Argentina, Departamento de Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina, Max Planck Institute of Psychiatry, 80804, Munich, Germany
⨯
[ view all ]
[ view less ]

Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function

Fernando Aprile-Garcia,
Michael W. Metzger,
Marcelo Paez-Pereda,
Herbert Stadler,
Matías Acuña,
Ana C. Liberman,
Sergio A. Senin,
Juan Gerez,
Esteban Hoijman,
Damian Refojo

Published: March 17, 2016
https://doi.org/10.1371/journal.pone.0151862

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Fluorescence resonance energy transfer
Is the Subject Area "Fluorescence resonance energy transfer" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Cell membranes
Is the Subject Area "Cell membranes" applicable to this article?

Thanks for your feedback.
Intracellular receptors
Is the Subject Area "Intracellular receptors" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Ligand-gated ion channels
Is the Subject Area "Ligand-gated ion channels" applicable to this article?

Thanks for your feedback.