Intrinsic Viral Factors Are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice

Open Access

Peer-reviewed

Research Article

Ran Chen ,

* E-mail: rchen3@ualberta.ca (RC); lorne.tyrrell@ualberta.ca (DLT)

Affiliations Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada, Li Ka Shing Institute of Virology, Katz Centre for Health Research, Edmonton, Alberta, Canada
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Michelle Kobewka,

Affiliations Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada, Li Ka Shing Institute of Virology, Katz Centre for Health Research, Edmonton, Alberta, Canada
⨯
William Addison,

Affiliations Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada, Li Ka Shing Institute of Virology, Katz Centre for Health Research, Edmonton, Alberta, Canada
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Gerald Lachance,

Affiliations Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada, Li Ka Shing Institute of Virology, Katz Centre for Health Research, Edmonton, Alberta, Canada
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D. Lorne Tyrrell

* E-mail: rchen3@ualberta.ca (RC); lorne.tyrrell@ualberta.ca (DLT)

Affiliations Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada, Li Ka Shing Institute of Virology, Katz Centre for Health Research, Edmonton, Alberta, Canada
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Mouse models
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Hepatocytes
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Interferons
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Hepatitis C virus
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Mammalian genomics
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Single nucleotide polymorphisms
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Animal models of infection
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Viremia
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