PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR

• Kyrill S. Rogacev ,

  * E-mail: kyrill.rogacev@uksh.de

  Affiliations Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany, Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Gunnar H. Heine,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Günther Silbernagel,

  Affiliation Division of Angiology, Swiss Cardiovascular Center, Bern University Hospital, Bern, Switzerland

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• Marcus E. Kleber,

  Affiliation Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

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• Sarah Seiler,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Insa Emrich,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Simone Lennartz,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Christian Werner,

  Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

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• Adam M. Zawada,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Danilo Fliser,

  Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

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• Michael Böhm,

  Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

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• Winfried März,

  Affiliations Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services GmbH, Mannheim and Augsburg, Germany, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria

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• Hubert Scharnagl ,

  Contributed equally to this work with: Hubert Scharnagl, Ulrich Laufs

  Affiliation Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria

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• Ulrich Laufs

  Contributed equally to this work with: Hubert Scharnagl, Ulrich Laufs

  Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

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