About the Authors

Kyrill S. Rogacev

kyrill.rogacev@uksh.de

Affiliations Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany, Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Gunnar H. Heine

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Günther Silbernagel

Affiliation Division of Angiology, Swiss Cardiovascular Center, Bern University Hospital, Bern, Switzerland

Marcus E. Kleber

Affiliation Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Sarah Seiler

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Insa Emrich

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Simone Lennartz

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Christian Werner

Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

Adam M. Zawada

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Danilo Fliser

Affiliation Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany

Michael Böhm

Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

Winfried März

Affiliations Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services GmbH, Mannheim and Augsburg, Germany, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria

Hubert Scharnagl

Contributed equally to this work with: Hubert Scharnagl, Ulrich Laufs

Affiliation Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria

Ulrich Laufs

Contributed equally to this work with: Hubert Scharnagl, Ulrich Laufs

Affiliation Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany

Competing Interests

WM is employed with synlab Services GmbH, Augsburg, Germany. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KSR GHH GS MEK SS IE SL CW AMZ DF MB WM HS UL. Performed the experiments: CW AMZ WM HS UL. Analyzed the data: KSR GHH GS MEK SS IE SL CW AMZ DF MB WM UL. Contributed reagents/materials/analysis tools: MEK CW WM HS UL. Wrote the paper: KSR GHH GS MEK CW WM HS UL.