The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila

Anne-Claire Jacomin; Amandine Bescond; Emmanuelle Soleilhac; Benoît Gallet; Guy Schoehn; Marie-Odile Fauvarque; Emmanuel Taillebourg

doi:10.1371/journal.pone.0143078

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Research Article

The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila

Anne-Claire Jacomin,

Current address: School of Life Sciences, University of Warwick, Coventry, United Kingdom

Affiliation Université Grenoble-Alpes, F-38041, Grenoble, France; CEA-DSV-iRTSV-BGE-Gen&Chem, F-38054, Grenoble, France; INSERM, U1038, F-38054, Grenoble, France
⨯
Amandine Bescond,

Affiliation Université Grenoble-Alpes, F-38041, Grenoble, France; CEA-DSV-iRTSV-BGE-Gen&Chem, F-38054, Grenoble, France; INSERM, U1038, F-38054, Grenoble, France
⨯
Emmanuelle Soleilhac,

Affiliation Université Grenoble-Alpes, F-38041, Grenoble, France; CEA-DSV-iRTSV-BGE-Gen&Chem, F-38054, Grenoble, France; INSERM, U1038, F-38054, Grenoble, France
⨯
Benoît Gallet,

Affiliation Université Grenoble Alpes, IBS, F-38044, Grenoble, France; CNRS, IBS, F-38044, Grenoble, France; CEA, IBS, F-38044, Grenoble, France
⨯
Guy Schoehn,

Affiliation Université Grenoble Alpes, IBS, F-38044, Grenoble, France; CNRS, IBS, F-38044, Grenoble, France; CEA, IBS, F-38044, Grenoble, France
⨯
Marie-Odile Fauvarque ,

* E-mail: emmanuel.taillebourg@cea.fr (ET); marie-odile.fauvarque@cea.fr (MOF)

Affiliation Université Grenoble-Alpes, F-38041, Grenoble, France; CEA-DSV-iRTSV-BGE-Gen&Chem, F-38054, Grenoble, France; INSERM, U1038, F-38054, Grenoble, France
⨯
Emmanuel Taillebourg

* E-mail: emmanuel.taillebourg@cea.fr (ET); marie-odile.fauvarque@cea.fr (MOF)

Affiliation Université Grenoble-Alpes, F-38041, Grenoble, France; CEA-DSV-iRTSV-BGE-Gen&Chem, F-38054, Grenoble, France; INSERM, U1038, F-38054, Grenoble, France
⨯

The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila

Anne-Claire Jacomin,
Amandine Bescond,
Emmanuelle Soleilhac,
Benoît Gallet,
Guy Schoehn,
Marie-Odile Fauvarque,
Emmanuel Taillebourg

Published: November 16, 2015
https://doi.org/10.1371/journal.pone.0143078

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Drosophila melanogaster
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