AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis

Open Access

Peer-reviewed

Research Article

Devadoss J. Samuvel,

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Nishant Saxena,

Affiliation Charles P. Darby Children’s Research Institute, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Jasdeep S. Dhindsa,

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Avtar K. Singh,

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Gurmit S. Gill,

Affiliation Akaal Pharma Pty Ltd., 310E Thomas Cherry Building, Bundoora, Australia
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Damian W. Grobelny,

Affiliation Akaal Pharma Pty Ltd., 310E Thomas Cherry Building, Bundoora, Australia
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Inderjit Singh

* E-mail: singhi@musc.edu

Affiliations Charles P. Darby Children’s Research Institute, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America, Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Lymphocytes
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Lymphopenia
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T cells
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Drug therapy
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Multiple sclerosis
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Central nervous system
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Cell membranes
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Adverse events
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