About the Authors

Devadoss J. Samuvel

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

Nishant Saxena

Affiliation Charles P. Darby Children’s Research Institute, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America

Jasdeep S. Dhindsa

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

Avtar K. Singh

Affiliation Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

Gurmit S. Gill

Affiliation Akaal Pharma Pty Ltd., 310E Thomas Cherry Building, Bundoora, Australia

Damian W. Grobelny

Affiliation Akaal Pharma Pty Ltd., 310E Thomas Cherry Building, Bundoora, Australia

Inderjit Singh

singhi@musc.edu

Affiliations Charles P. Darby Children’s Research Institute, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America, Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

Competing Interests

GSG and DWG are employed by Akaal Pharma Pty Ltd.. Akaal Pharma Pty Ltd. provided the drug AKP-11 for this study. There are no patents, further products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DJS IS. Performed the experiments: DJS NS JSD. Analyzed the data: DJS NS AKS IS. Contributed reagents/materials/analysis tools: IS AKS GSG DWG. Wrote the paper: DJS NS IS.