In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells

• Sarada Devi Ramachandran,

  Affiliation Medicyte GmbH, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany

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• Katharina Schirmer,

  Affiliation Department of Medicine II, Faculty of Medicine at Mannheim, Heidelberg University, Mannheim, Germany

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• Bernhard Münst,

  Affiliation Medicyte GmbH, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany

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• Stefan Heinz,

  Affiliations Medicyte GmbH, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany, upcyte technologies GmbH, Osterfeldstraße 12–14, 22529, Hamburg, Germany

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• Shahrouz Ghafoory,

  Affiliation Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany

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• Stefan Wölfl,

  Affiliation Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany

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• Katja Simon-Keller,

  Affiliation Institute of Pathology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

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• Alexander Marx,

  Affiliation Institute of Pathology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

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• Cristina Ionica Øie,

  Affiliation Vascular Biology Research Group, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Sykehusgt. 44, N–9037, Tromsø, Norway

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• Matthias P. Ebert,

  Affiliation Department of Medicine II, Faculty of Medicine at Mannheim, Heidelberg University, Mannheim, Germany

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• Heike Walles,

  Affiliation Tissue Engineering and Regenerative Medicine, University Wuerzburg, Roentgenring 11, 97070, Würzburg, Germany

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• Joris Braspenning ,

  Contributed equally to this work with: Joris Braspenning, Katja Breitkopf-Heinlein

  Affiliation Medicyte GmbH, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany

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• Katja Breitkopf-Heinlein

  Contributed equally to this work with: Joris Braspenning, Katja Breitkopf-Heinlein

  * E-mail: katja.breitkopf@medma.uni-heidelberg.de

  Affiliation Department of Medicine II, Faculty of Medicine at Mannheim, Heidelberg University, Mannheim, Germany

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