Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

• Mun Chiang Chan,

  Affiliations Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom, Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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• Onur Atasoylu,

  Current Address: School of Pharmacy, University of East Anglia, Norwich, Norfolk, United Kingdom

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Emma Hodson,

  Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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• Anthony Tumber,

  Affiliation Target Discovery Institute, University of Oxford, Oxford, United Kingdom

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• Ivanhoe K. H. Leung,

  Current Address: School of Chemical Sciences, University of Auckland, Auckland, New Zealand

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Rasheduzzaman Chowdhury,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Verónica Gómez-Pérez,

  Current Address: Instituto de Parasitología y Biomedicina "López-Neyra", IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Marina Demetriades,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Anna M. Rydzik,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• James Holt-Martyn,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Ya-Min Tian,

  Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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• Tammie Bishop,

  Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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• Timothy D. W. Claridge,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Akane Kawamura,

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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• Christopher W. Pugh,

  Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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• Peter J. Ratcliffe,

  Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

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•  [ ... ],
• Christopher J. Schofield

  * E-mail: christopher.schofield@chem.ox.ac.uk

  Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

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