About the Authors

Mun Chiang Chan

Affiliations Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom, Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Onur Atasoylu

Current Address: School of Pharmacy, University of East Anglia, Norwich, Norfolk, United Kingdom

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Emma Hodson

Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Anthony Tumber

Affiliation Target Discovery Institute, University of Oxford, Oxford, United Kingdom

Ivanhoe K. H. Leung

Current Address: School of Chemical Sciences, University of Auckland, Auckland, New Zealand

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Rasheduzzaman Chowdhury

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Verónica Gómez-Pérez

Current Address: Instituto de Parasitología y Biomedicina "López-Neyra", IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Marina Demetriades

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Anna M. Rydzik

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

James Holt-Martyn

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Ya-Min Tian

Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Tammie Bishop

Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Timothy D. W. Claridge

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Akane Kawamura

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Christopher W. Pugh

Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Peter J. Ratcliffe

Affiliation Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom

Christopher J. Schofield

christopher.schofield@chem.ox.ac.uk

Affiliation Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MCC EH AT IKHL RC TB TDWC AK CWP PJR CJS. Performed the experiments: MCC OA EH AT IKHL RC VG MD AR JH TB. Analyzed the data: MCC OA EH AT IKHL RC VG MD AR JH YT TB TDWC AK CWP PJR CJS. Wrote the paper: MCC CJS.