Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices

Ulrika Johansson; Massimiliano Ria; Karin Åvall; Nancy Dekki Shalaly; Sergei V. Zaitsev; Per-Olof Berggren; My Hedhammar

doi:10.1371/journal.pone.0130169

Loading metrics

Open Access

Peer-reviewed

Research Article

Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices

Ulrika Johansson,

Affiliations Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, the Biomedical Centre, S-750 07, Uppsala, Sweden, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, S-171 76 Stockholm, Sweden
⨯
Massimiliano Ria ,

Contributed equally to this work with: Massimiliano Ria, Karin Åvall

Affiliation The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, S-171 76 Stockholm, Sweden
⨯
Karin Åvall ,

Contributed equally to this work with: Massimiliano Ria, Karin Åvall

Affiliation The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, S-171 76 Stockholm, Sweden
⨯
Nancy Dekki Shalaly,

Affiliation Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, S-106 91 Stockholm, Sweden
⨯
Sergei V. Zaitsev ,

* E-mail: My.Hedhammar@slu.se (MH); Sergei.Zaitsev@ki.se (SVZ)

Affiliation The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, S-171 76 Stockholm, Sweden
⨯
Per-Olof Berggren,

Affiliation The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, S-171 76 Stockholm, Sweden
⨯
My Hedhammar

* E-mail: My.Hedhammar@slu.se (MH); Sergei.Zaitsev@ki.se (SVZ)

Affiliations Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, the Biomedical Centre, S-750 07, Uppsala, Sweden, Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, S-106 91 Stockholm, Sweden
⨯

Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices

Ulrika Johansson,
Massimiliano Ria,
Karin Åvall,
Nancy Dekki Shalaly,
Sergei V. Zaitsev,
Per-Olof Berggren,
My Hedhammar

Published: June 19, 2015
https://doi.org/10.1371/journal.pone.0130169

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Foams
Is the Subject Area "Foams" applicable to this article?

Thanks for your feedback.
Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.
Eyes
Is the Subject Area "Eyes" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Islet transplantation
Is the Subject Area "Islet transplantation" applicable to this article?

Thanks for your feedback.
Endothelial cells
Is the Subject Area "Endothelial cells" applicable to this article?

Thanks for your feedback.
Extracellular matrix
Is the Subject Area "Extracellular matrix" applicable to this article?

Thanks for your feedback.
Spiders
Is the Subject Area "Spiders" applicable to this article?

Thanks for your feedback.