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Open Access
Peer-reviewed
Research Article
Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay
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Satoshi Yoshimi ,
Contributed equally to this work with: Satoshi Yoshimi, Hidenori Ochi
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Hidenori Ochi ,
Contributed equally to this work with: Satoshi Yoshimi, Hidenori Ochi
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Eisuke Murakami,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Takuro Uchida,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Hiromi Kan,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Sakura Akamatsu,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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C. Nelson Hayes,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Hiromi Abe,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Daiki Miki,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Nobuhiko Hiraga,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Michio Imamura,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Hiroshi Aikata,
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Kazuaki Chayama
* E-mail: chayama@hiroshima-u.ac.jp
Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan
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Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay
- Satoshi Yoshimi,
- Hidenori Ochi,
- Eisuke Murakami,
- Takuro Uchida,
- Hiromi Kan,
- Sakura Akamatsu,
- C. Nelson Hayes,
- Hiromi Abe,
- Daiki Miki,
- Nobuhiko Hiraga
- Published: June 17, 2015
- https://doi.org/10.1371/journal.pone.0130022