About the Authors

Satoshi Yoshimi

Contributed equally to this work with: Satoshi Yoshimi, Hidenori Ochi

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Hidenori Ochi

Contributed equally to this work with: Satoshi Yoshimi, Hidenori Ochi

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Eisuke Murakami

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Takuro Uchida

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Hiromi Kan

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Sakura Akamatsu

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

C. Nelson Hayes

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Hiromi Abe

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Daiki Miki

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Nobuhiko Hiraga

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Michio Imamura

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Hiroshi Aikata

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Kazuaki Chayama

chayama@hiroshima-u.ac.jp

Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SY HO DM MI KC. Performed the experiments: SY HO EM TU HK H.Abe NH. Analyzed the data: SY HO EM TU HK SA NH CNH. Contributed reagents/materials/analysis tools: HO DM CNH MI H. Aikata KC. Wrote the paper: SY HO CNH KC.