Three Huntington’s Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes

Laureen Jacquet; Andreas Neueder; Gabor Földes; Panagiotis Karagiannis; Carl Hobbs; Nelly Jolinon; Maxime Mioulane; Takao Sakai; Sian E. Harding; Dusko Ilic

doi:10.1371/journal.pone.0126860

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Peer-reviewed

Research Article

Three Huntington’s Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes

Laureen Jacquet,

Affiliation Stem Cell Laboratory, Assisted Conception Unit, Division of Women’s Health, King’s College London, Guy's Hospital, London, SE1 9RT, United Kingdom
⨯
Andreas Neueder,

Affiliation Division of Genetics and Molecular Medicine, King's College London, Guy's Hospital, London, SE1 9RT, United Kingdom
⨯
Gabor Földes,

Affiliation National Heart and Lung Institute, Imperial College, ICTEM, 4th Floor, Hammersmith Campus, Du Cane Rd, London, W12 0NN, United Kingdom
⨯
Panagiotis Karagiannis,

Affiliation Division of Genetics and Molecular Medicine, King's College London, Guy's Hospital, London, SE1 9RT, United Kingdom
⨯
Carl Hobbs,

Affiliation Histology Laboratory, Wolfson Centre for Age-Related Diseases, King's College London, London, SE1 1UL, United Kingdom
⨯
Nelly Jolinon,

Affiliation Division of Genetics and Molecular Medicine, King's College London, Guy's Hospital, London, SE1 9RT, United Kingdom
⨯
Maxime Mioulane,

Affiliation National Heart and Lung Institute, Imperial College, ICTEM, 4th Floor, Hammersmith Campus, Du Cane Rd, London, W12 0NN, United Kingdom
⨯
Takao Sakai,

Affiliation Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, L69 3GE, United Kingdom
⨯
Sian E. Harding,

Affiliation National Heart and Lung Institute, Imperial College, ICTEM, 4th Floor, Hammersmith Campus, Du Cane Rd, London, W12 0NN, United Kingdom
⨯
Dusko Ilic

* E-mail: dusko.ilic@kcl.ac.uk

Affiliation Stem Cell Laboratory, Assisted Conception Unit, Division of Women’s Health, King’s College London, Guy's Hospital, London, SE1 9RT, United Kingdom
⨯

Three Huntington’s Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes

Laureen Jacquet,
Andreas Neueder,
Gabor Földes,
Panagiotis Karagiannis,
Carl Hobbs,
Nelly Jolinon,
Maxime Mioulane,
Takao Sakai,
Sian E. Harding,
Dusko Ilic

Published: May 20, 2015
https://doi.org/10.1371/journal.pone.0126860

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