Snooker Structure-Based Pharmacophore Model Explains Differences in Agonist and Blocker Binding to Bitter Receptor hTAS2R39

• Wibke S. U. Roland,

  Current address: NIZO food research, 6718 ZB Ede, The Netherlands

  Affiliation Laboratory of Food Chemistry, Wageningen University, 6708 WG Wageningen, The Netherlands

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• Marijn P. A. Sanders,

  Current address: Aorta business intelligence, 5145 RM Waalwijk, The Netherlands

  Affiliation Computational Discovery and Design Group (CDD), Centre for Molecular and Biomolecular Informatics (CMBI), Radboud university medical center, 6500 HB Nijmegen, The Netherlands

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• Leo van Buren,

  Affiliation Unilever R&D, 3133 AT Vlaardingen, The Netherlands

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• Robin J. Gouka,

  Affiliation Unilever R&D, 3133 AT Vlaardingen, The Netherlands

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• Harry Gruppen,

  Affiliation Laboratory of Food Chemistry, Wageningen University, 6708 WG Wageningen, The Netherlands

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• Jean-Paul Vincken,

  Affiliation Laboratory of Food Chemistry, Wageningen University, 6708 WG Wageningen, The Netherlands

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• Tina Ritschel

  * E-mail: tina.ritschel@radboudumc.nl

  Affiliation Computational Discovery and Design Group (CDD), Centre for Molecular and Biomolecular Informatics (CMBI), Radboud university medical center, 6500 HB Nijmegen, The Netherlands

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