Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture

• Akira Shimamoto ,

  * E-mail: shim@hiroshima-u.ac.jp (AS); toshi@hiroshima-u.ac.jp (HT)

  Affiliation Department of Cellular and Molecular Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Harunobu Kagawa,

  Affiliation Department of Cellular and Molecular Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Kazumasa Zensho,

  Affiliation Department of Cellular and Molecular Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Yukihiro Sera,

  Affiliation Department of Cellular and Molecular Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Yasuhiro Kazuki,

  Affiliation Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Japan

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• Mitsuhiko Osaki,

  Affiliations Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Japan, Division of Pathological Biochemistry, Faculty of Medicine, Tottori University, Yonago, Japan

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• Mitsuo Oshimura,

  Affiliation Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Japan

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• Yasuhito Ishigaki,

  Affiliation Medical Research Institute, Kanazawa Medical University, Kahoku, Ishikawa, Japan

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• Kanya Hamasaki,

  Affiliation Department of Genetics, Radiation Effects Research Foundation, Hiroshima, Japan

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• Yoshiaki Kodama,

  Affiliation Department of Genetics, Radiation Effects Research Foundation, Hiroshima, Japan

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• Shinsuke Yuasa,

  Affiliation Department of Cardiology, Keio University School of Medicine, Tokyo, Japan

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• Keiichi Fukuda,

  Affiliation Department of Cardiology, Keio University School of Medicine, Tokyo, Japan

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• Kyotaro Hirashima,

  Affiliation Division of Molecular Biotherapy, The Cancer Chemotherapy Center, Japanese Foundation For Cancer Research, Tokyo, Japan

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• Hiroyuki Seimiya,

  Affiliation Division of Molecular Biotherapy, The Cancer Chemotherapy Center, Japanese Foundation For Cancer Research, Tokyo, Japan

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• Hirofumi Koyama,

  Affiliation Department of Advanced Aging Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

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• Takahiko Shimizu,

  Affiliation Department of Advanced Aging Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

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• Minoru Takemoto,

  Affiliation Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

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• Koutaro Yokote,

  Affiliation Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

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• Makoto Goto,

  Affiliation Division of Orthopedic Surgery & Rheumatology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan

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•  [ ... ],
• Hidetoshi Tahara

  * E-mail: shim@hiroshima-u.ac.jp (AS); toshi@hiroshima-u.ac.jp (HT)

  Affiliation Department of Cellular and Molecular Biology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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