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Open Access
Peer-reviewed
Research Article
Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures
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Nuno Jorge Lamas,
Affiliations Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, New York, United States of America, Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Department of Neurology, Columbia University Medical Center, New York, New York, United States of America, Department of Neuroscience, Columbia University Medical Center, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, United States of America, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, New York, United States of America, Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Minho, Portugal, ICVS/3B’s-PT Government Associate Laboratory, Braga/Guimarães, Minho, Portugal
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Bethany Johnson-Kerner,
Affiliations Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, New York, United States of America, Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Department of Neurology, Columbia University Medical Center, New York, New York, United States of America, Department of Neuroscience, Columbia University Medical Center, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, United States of America, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, New York, United States of America
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Laurent Roybon,
Current address: Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Skåne, Sweden
Affiliations Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, New York, United States of America, Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Department of Neurology, Columbia University Medical Center, New York, New York, United States of America, Department of Neuroscience, Columbia University Medical Center, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, United States of America, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, New York, United States of America
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Yoon A. Kim,
Affiliation Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America
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Alejandro Garcia-Diaz,
Affiliation Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America
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Hynek Wichterle,
Affiliations Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, New York, United States of America, Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Department of Neurology, Columbia University Medical Center, New York, New York, United States of America, Department of Neuroscience, Columbia University Medical Center, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, United States of America, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, New York, United States of America
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Christopher E. Henderson
* E-mail: ch2331@columbia.edu
Affiliations Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, New York, New York, United States of America, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, New York, United States of America, Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Department of Neurology, Columbia University Medical Center, New York, New York, United States of America, Department of Neuroscience, Columbia University Medical Center, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, United States of America, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, New York, United States of America
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Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures
- Nuno Jorge Lamas,
- Bethany Johnson-Kerner,
- Laurent Roybon,
- Yoon A. Kim,
- Alejandro Garcia-Diaz,
- Hynek Wichterle,
- Christopher E. Henderson
- Published: October 22, 2014
- https://doi.org/10.1371/journal.pone.0110324