Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

• Karyn J. Catalano,

  Affiliation Department of Obstetrics and Gynecology and the Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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• Betty A. Maddux,

  Affiliations Department of Obstetrics and Gynecology and the Diabetes Center, University of California San Francisco, San Francisco, California, United States of America, Division of Endocrinology and Metabolism, University of California San Francisco, San Francisco, California, United States of America

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• Jaroslaw Szary,

  Affiliation Department of Obstetrics and Gynecology and the Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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• Jack F. Youngren,

  Affiliation Division of Endocrinology and Metabolism, University of California San Francisco, San Francisco, California, United States of America

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• Ira D. Goldfine,

  Affiliation Division of Endocrinology and Metabolism, University of California San Francisco, San Francisco, California, United States of America

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• Fred Schaufele

  * E-mail: freds@diabetes.ucsf.edu

  Affiliation Department of Obstetrics and Gynecology and the Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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