Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour Growth in Immunocompetent Murine Models

Bérengère Gobin; Gatien Moriceau; Benjamin Ory; Céline Charrier; Régis Brion; Frederic Blanchard; Françoise Redini; Dominique Heymann

doi:10.1371/journal.pone.0090795

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Peer-reviewed

Research Article

Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour Growth in Immunocompetent Murine Models

Bérengère Gobin ,

Contributed equally to this work with: Bérengère Gobin, Gatien Moriceau

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France
⨯
Gatien Moriceau ,

Contributed equally to this work with: Bérengère Gobin, Gatien Moriceau

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France
⨯
Benjamin Ory,

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France
⨯
Céline Charrier,

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France
⨯
Régis Brion,

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France, CHU de Nantes, Nantes, France
⨯
Frederic Blanchard,

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France
⨯
Françoise Redini,

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France, CHU de Nantes, Nantes, France
⨯
Dominique Heymann

* E-mail: dominique.heymann@univ-nantes.fr

Affiliations INSERM, UMR 957, Nantes, France, Université de Nantes, Nantes Atlantique Universités, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France, CHU de Nantes, Nantes, France
⨯

Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour Growth in Immunocompetent Murine Models

Bérengère Gobin,
Gatien Moriceau,
Benjamin Ory,
Céline Charrier,
Régis Brion,
Frederic Blanchard,
Françoise Redini,
Dominique Heymann

Published: March 5, 2014
https://doi.org/10.1371/journal.pone.0090795

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