Sweet Taste Receptor Deficient Mice Have Decreased Adiposity and Increased Bone Mass

Becky R. Simon; Brian S. Learman; Sebastian D. Parlee; Erica L. Scheller; Hiroyuki Mori; William P. Cawthorn; Xiaomin Ning; Venkatesh Krishnan; Yanfei L. Ma; Björn Tyrberg; Ormond A. MacDougald

doi:10.1371/journal.pone.0086454

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Open Access

Peer-reviewed

Research Article

Sweet Taste Receptor Deficient Mice Have Decreased Adiposity and Increased Bone Mass

Becky R. Simon,

Affiliation Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Brian S. Learman,

Affiliation Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Sebastian D. Parlee,

Affiliation Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Erica L. Scheller,

Affiliation Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Hiroyuki Mori,

Affiliation Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
William P. Cawthorn,

Affiliations Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, Musculoskeletal Research, Lilly Research Laboratories, Indianapolis, Indiana, United States of America
⨯
Xiaomin Ning,

Affiliation Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Venkatesh Krishnan,

Affiliation Musculoskeletal Research, Lilly Research Laboratories, Indianapolis, Indiana, United States of America
⨯
Yanfei L. Ma,

Affiliation Musculoskeletal Research, Lilly Research Laboratories, Indianapolis, Indiana, United States of America
⨯
Björn Tyrberg,

Affiliations Cardiovascular and Metabolic Disease, MedImmune LLC, Gaithersburg, Maryland, United States of America, Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida, United States of America
⨯
Ormond A. MacDougald

* E-mail: macdouga@umich.edu

Affiliations Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
⨯

Sweet Taste Receptor Deficient Mice Have Decreased Adiposity and Increased Bone Mass

Becky R. Simon,
Brian S. Learman,
Sebastian D. Parlee,
Erica L. Scheller,
Hiroyuki Mori,
William P. Cawthorn,
Xiaomin Ning,
Venkatesh Krishnan,
Yanfei L. Ma,
Björn Tyrberg

Published: January 22, 2014
https://doi.org/10.1371/journal.pone.0086454

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