Variance in Brain Volume with Advancing Age: Implications for Defining the Limits of Normality

David Alexander Dickie; Dominic E. Job; David Rodriguez Gonzalez; Susan D. Shenkin; Trevor S. Ahearn; Alison D. Murray; Joanna M. Wardlaw

doi:10.1371/journal.pone.0084093

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Open Access

Peer-reviewed

Research Article

Variance in Brain Volume with Advancing Age: Implications for Defining the Limits of Normality

David Alexander Dickie,

Affiliations Brain Research Imaging Centre (BRIC), The University of Edinburgh, Neuroimaging Sciences, Western General Hospital, Edinburgh, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
Dominic E. Job ,

* E-mail: Dominic.Job@ed.ac.uk

Affiliations Brain Research Imaging Centre (BRIC), The University of Edinburgh, Neuroimaging Sciences, Western General Hospital, Edinburgh, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
David Rodriguez Gonzalez,

Affiliations Brain Research Imaging Centre (BRIC), The University of Edinburgh, Neuroimaging Sciences, Western General Hospital, Edinburgh, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
Susan D. Shenkin,

Affiliations Geriatric Medicine Unit, The University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
Trevor S. Ahearn,

Affiliations Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
Alison D. Murray,

Affiliations Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯
Joanna M. Wardlaw

Affiliations Brain Research Imaging Centre (BRIC), The University of Edinburgh, Neuroimaging Sciences, Western General Hospital, Edinburgh, United Kingdom, Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) collaboration, Edinburgh, United Kingdom
⨯

Variance in Brain Volume with Advancing Age: Implications for Defining the Limits of Normality

David Alexander Dickie,
Dominic E. Job,
David Rodriguez Gonzalez,
Susan D. Shenkin,
Trevor S. Ahearn,
Alison D. Murray,
Joanna M. Wardlaw

Published: December 19, 2013
https://doi.org/10.1371/journal.pone.0084093

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