TGFβ1 Polymorphisms Predict Distant Metastasis–Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy

Xianglin Yuan; Qingyi Wei; Ritsuko Komaki; Zhensheng Liu; Ju Yang; Susan L. Tucker; Ting Xu; John V. Heymach; Charles Lu; James D. Cox; Zhongxing Liao

doi:10.1371/journal.pone.0065659

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Open Access

Peer-reviewed

Research Article

TGFβ1 Polymorphisms Predict Distant Metastasis–Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy

Xianglin Yuan,

Affiliation Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Qingyi Wei,

Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ritsuko Komaki,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Zhensheng Liu,

Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ju Yang,

Affiliation Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Susan L. Tucker,

Affiliation Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ting Xu,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
John V. Heymach,

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Charles Lu,

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
James D. Cox,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Zhongxing Liao

* E-mail: zliao@mdanderson.org

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯

TGFβ1 Polymorphisms Predict Distant Metastasis–Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy

Xianglin Yuan,
Qingyi Wei,
Ritsuko Komaki,
Zhensheng Liu,
Ju Yang,
Susan L. Tucker,
Ting Xu,
John V. Heymach,
Charles Lu,
James D. Cox

Published: June 19, 2013
https://doi.org/10.1371/journal.pone.0065659

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Non-small cell lung cancer
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Radiation therapy
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Variant genotypes
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Single nucleotide polymorphisms
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