Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro

Jing Sun; Guibo Sun; Xiangbao Meng; Hongwei Wang; Yun Luo; Meng Qin; Bo Ma; Min Wang; Dayong Cai; Peng Guo; Xiaobo Sun

doi:10.1371/journal.pone.0064526

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Open Access

Peer-reviewed

Research Article

Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro

Jing Sun,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Guibo Sun ,

* E-mail: sun_xiaobo163@163.com (XS); sunguibo@126.com (GS)

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Xiangbao Meng,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Hongwei Wang,

Affiliation Center for Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, Jiangsu, P. R. China
⨯
Yun Luo,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Meng Qin,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Bo Ma,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Min Wang,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Dayong Cai,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Peng Guo,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯
Xiaobo Sun

* E-mail: sun_xiaobo163@163.com (XS); sunguibo@126.com (GS)

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
⨯

Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro

Jing Sun,
Guibo Sun,
Xiangbao Meng,
Hongwei Wang,
Yun Luo,
Meng Qin,
Bo Ma,
Min Wang,
Dayong Cai,
Peng Guo

Published: May 28, 2013
https://doi.org/10.1371/journal.pone.0064526

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