Genome-Scale Screening of Drug-Target Associations Relevant to Ki Using a Chemogenomics Approach

Dong-Sheng Cao; Yi-Zeng Liang; Zhe Deng; Qian-Nan Hu; Min He; Qing-Song Xu; Guang-Hua Zhou; Liu-Xia Zhang; Zi-xin Deng; Shao Liu

doi:10.1371/journal.pone.0057680

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Open Access

Peer-reviewed

Research Article

Genome-Scale Screening of Drug-Target Associations Relevant to K_i Using a Chemogenomics Approach

Dong-Sheng Cao,

Affiliation Research Center of Modernization of Traditional Chinese Medicines, Central South University, Changsha, P. R. China
⨯
Yi-Zeng Liang ,

* E-mail: yizeng_liang@263.net (YZL); qnhu@whu.edu.cn (QNH)

Affiliation Research Center of Modernization of Traditional Chinese Medicines, Central South University, Changsha, P. R. China
⨯
Zhe Deng,

Affiliation Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan, P. R. China
⨯
Qian-Nan Hu ,

* E-mail: yizeng_liang@263.net (YZL); qnhu@whu.edu.cn (QNH)

Affiliation Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan, P. R. China
⨯
Min He,

Affiliation Research Center of Modernization of Traditional Chinese Medicines, Central South University, Changsha, P. R. China
⨯
Qing-Song Xu,

Affiliation School of Mathematics and Statistics, Central South University, Changsha, P. R. China
⨯
Guang-Hua Zhou,

Affiliation The 163rd Hospital of The Chinese People's Liberation Army, Changsha, P. R. China
⨯
Liu-Xia Zhang,

Affiliation The 163rd Hospital of The Chinese People's Liberation Army, Changsha, P. R. China
⨯
Zi-xin Deng,

Affiliation Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan, P. R. China
⨯
Shao Liu

Affiliation Xiangya Hospital, Central South University, Changsha, P. R. China
⨯

Genome-Scale Screening of Drug-Target Associations Relevant to K_i Using a Chemogenomics Approach

Dong-Sheng Cao,
Yi-Zeng Liang,
Zhe Deng,
Qian-Nan Hu,
Min He,
Qing-Song Xu,
Guang-Hua Zhou,
Liu-Xia Zhang,
Zi-xin Deng,
Shao Liu

Published: April 5, 2013
https://doi.org/10.1371/journal.pone.0057680

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