Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): The Influence of Gender and Genetics (CYP2D6, COMT, 5-HTT)

• Ricardo Pardo-Lozano ,

  Contributed equally to this work with: Ricardo Pardo-Lozano, Magí Farré, Samanta Yubero-Lahoz

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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• Magí Farré ,

  Contributed equally to this work with: Ricardo Pardo-Lozano, Magí Farré, Samanta Yubero-Lahoz

  * E-mail: mfarre@imim.es

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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• Samanta Yubero-Lahoz ,

  Contributed equally to this work with: Ricardo Pardo-Lozano, Magí Farré, Samanta Yubero-Lahoz

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Pompeu Fabra (CEXS-UPF), Barcelona, Spain

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• Brian O’Mathúna,

  Affiliation Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain

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• Marta Torrens,

  Affiliations Universitat Autònoma de Barcelona (UAB), Barcelona, Spain, Disorders by Use of Substances Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), INAD-Hospital del Mar, Parc de Salut Mar, Barcelona, Spain

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• Cristina Mustata,

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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• Clara Pérez-Mañá,

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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• Klaus Langohr,

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Department of Statistics and Operational Research, Universitat Politècnica de Catalunya, Barcelona, Spain

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• Elisabet Cuyàs,

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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• Marcel·lí Carbó,

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Pompeu Fabra (CEXS-UPF), Barcelona, Spain

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• Rafael de la Torre

  Affiliations Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Parc de Salut Mar, Barcelona, Spain, Universitat Pompeu Fabra (CEXS-UPF), Barcelona, Spain, CIBER de Fisiopatología de la Obesidad y Nutrición (CB06/03), CIBEROBN, Santiago de Compostela, Spain

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