Fractionation of a Herbal Antidiarrheal Medicine Reveals Eugenol as an Inhibitor of Ca²⁺-Activated Cl⁻ Channel TMEM16A

• Zhen Yao,

  Affiliation Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• Wan Namkung,

  Affiliations Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America, Yonsei University, College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Incheon, Korea

  ⨯
• Eun A. Ko,

  Affiliation Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• Jinhong Park,

  Affiliation Yonsei University, College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Incheon, Korea

  ⨯
• Lukmanee Tradtrantip,

  Affiliation Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• A. S. Verkman

  * E-mail: Alan.Verkman@ucsf.edu

  Affiliation Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America

  ⨯