Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells

Isabelle E. Vincent; Claudia Zannetti; Julie Lucifora; Helene Norder; Ulrike Protzer; Pierre Hainaut; Fabien Zoulim; Massimo Tommasino; Christian Trépo; Uzma Hasan; Isabelle Chemin

doi:10.1371/journal.pone.0026315

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Open Access

Peer-reviewed

Research Article

Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells

Isabelle E. Vincent ,

Contributed equally to this work with: Isabelle E. Vincent, Claudia Zannetti

* E-mail: isabelle.vincent@inserm.fr

Affiliations INSERM, U871, Lyon, France, Université Lyon 1, Lyon, France
⨯
Claudia Zannetti ,

Contributed equally to this work with: Isabelle E. Vincent, Claudia Zannetti

Affiliations Université Lyon 1, Lyon, France, INSERM, U851, Faculte de Medicine Lyon Sud, Pierre Benite, France, Hospices Civils de Lyon, Lyon, France
⨯
Julie Lucifora,

Affiliation Institute of Virology, Technische Universität München, Helmholtz Zentrum München, Munich, Germany
⨯
Helene Norder,

Affiliation Virological Department, Swedish Institute for Infectious Disease Control, Solna, Sweden
⨯
Ulrike Protzer,

Affiliation Institute of Virology, Technische Universität München, Helmholtz Zentrum München, Munich, Germany
⨯
Pierre Hainaut,

Affiliation International Agency for Research on Cancer, Lyon, France
⨯
Fabien Zoulim,

Affiliations INSERM, U871, Lyon, France, Université Lyon 1, Lyon, France, Hospices Civils de Lyon, Lyon, France
⨯
Massimo Tommasino,

Affiliation International Agency for Research on Cancer, Lyon, France
⨯
Christian Trépo,

Affiliations INSERM, U871, Lyon, France, Université Lyon 1, Lyon, France, Hospices Civils de Lyon, Lyon, France
⨯
Uzma Hasan,

Affiliations Université Lyon 1, Lyon, France, INSERM, U851, Faculte de Medicine Lyon Sud, Pierre Benite, France, Hospices Civils de Lyon, Lyon, France
⨯
Isabelle Chemin

Affiliations INSERM, U871, Lyon, France, Université Lyon 1, Lyon, France
⨯

Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells

Isabelle E. Vincent,
Claudia Zannetti,
Julie Lucifora,
Helene Norder,
Ulrike Protzer,
Pierre Hainaut,
Fabien Zoulim,
Massimo Tommasino,
Christian Trépo,
Uzma Hasan

Published: October 25, 2011
https://doi.org/10.1371/journal.pone.0026315

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Virions
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Toll-like receptors
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Secretion
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B cells
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Hepatitis B virus
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Hepatitis B
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