A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier

• Delara Karkan ,

  Contributed equally to this work with: Delara Karkan, Timothy Z. Vitalis

  Current address: Centre for Evaluation of Radiopharmaceuticals and Biotherapeutics, Ottawa, Ontario, Canada,

  Affiliation BioMarin Pharmaceutical Inc., Vancouver, Canada

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• Cheryl Pfeifer ,

  * E-mail: wilf@brc.ubc.ca

  Affiliations Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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• Timothy Z. Vitalis ,

  Contributed equally to this work with: Delara Karkan, Timothy Z. Vitalis

  Current address: The Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada,

  Affiliations BioMarin Pharmaceutical Inc., Vancouver, Canada, Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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• Gavin Arthur ,

  * E-mail: wilf@brc.ubc.ca

  Current address: Genome British Columbia, Vancouver, British Columbia, Canada,

  Affiliation BioMarin Pharmaceutical Inc., Vancouver, Canada

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• Maki Ujiie ,

  * E-mail: wilf@brc.ubc.ca

  Affiliations Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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• Qingqi Chen,

  Current address: BioMarin Pharmaceutical Inc., Novato, California, United States of America,

  Affiliation BioMarin Pharmaceutical Inc., Vancouver, Canada

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• Sam Tsai,

  Current address: University of Alberta, Edmonton, Alberta, Canada,

  Affiliation BioMarin Pharmaceutical Inc., Vancouver, Canada

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• Gerrasimo Koliatis,

  Current address: Roche Pharmaceuticals, Nutley, New Jersey, United States of America,

  Affiliations BioMarin Pharmaceutical Inc., Vancouver, Canada, Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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• Reinhard Gabathuler,

  Current address: AngioChem Inc., Montreal, Quebec, Canada

  Affiliations BioMarin Pharmaceutical Inc., Vancouver, Canada, Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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• Wilfred A. Jefferies

  * E-mail: wilf@brc.ubc.ca

  Affiliations Department of Medical Genetics, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada, Department of Zoology, the Michael Smith Laboratories and the Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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