PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells

Chee Gee Liew; Nadia N. Shah; Sarah J. Briston; Ruth M. Shepherd; Cheen Peen Khoo; Mark J. Dunne; Harry D. Moore; Karen E. Cosgrove; Peter W. Andrews

doi:10.1371/journal.pone.0001783

Loading metrics

Open Access

Peer-reviewed

Research Article

PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells

Chee Gee Liew,

Current address: UCI Stem Cell Research Center, University of California Irvine, Irvine, California, United States of America

Affiliations Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, United Kingdom, Centre for Stem Cell Biology, Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, United Kingdom
⨯
Nadia N. Shah ,

Contributed equally to this work with: Nadia N. Shah, Sarah J. Briston

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Sarah J. Briston ,

Contributed equally to this work with: Nadia N. Shah, Sarah J. Briston

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Ruth M. Shepherd,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Cheen Peen Khoo,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Mark J. Dunne,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Harry D. Moore,

Affiliations Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, United Kingdom, Centre for Stem Cell Biology, Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, United Kingdom
⨯
Karen E. Cosgrove ,

* E-mail: karen.e.cosgrove@manchester.ac.uk (KC); p.w.andrews@sheffield.ac.uk (PA)

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Peter W. Andrews

* E-mail: karen.e.cosgrove@manchester.ac.uk (KC); p.w.andrews@sheffield.ac.uk (PA)

Affiliations Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, United Kingdom, Centre for Stem Cell Biology, Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, United Kingdom
⨯

PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells

Chee Gee Liew,
Nadia N. Shah,
Sarah J. Briston,
Ruth M. Shepherd,
Cheen Peen Khoo,
Mark J. Dunne,
Harry D. Moore,
Karen E. Cosgrove,
Peter W. Andrews

Published: March 12, 2008
https://doi.org/10.1371/journal.pone.0001783

Reader Comments (1)

Post a new comment on this article

0 Responses

18 Mar 2008
10:20 GMT
Most Recent

Referee comments: Referee 2 Posted by PLOS_ONE_Group on 18 Mar 2008 at 10:20 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Endoderm
Is the Subject Area "Endoderm" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.