Association between CASP8 –652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study

Barbara Pardini; Paolo Verderio; Sara Pizzamiglio; Carmela Nici; Maria Valeria Maiorana; Alessio Naccarati; Ludmila Vodickova; Veronika Vymetalkova; Silvia Veneroni; Maria Grazia Daidone; Fernando Ravagnani; Tiziana Bianchi; Luis Bujanda; Angel Carracedo; Antoni Castells; Clara Ruiz-Ponte; Hans Morreau; Kimberley Howarth; Angela Jones; Sergi Castellví-Bel; Li Li; Ian Tomlinson; Tom Van Wezel; Pavel Vodicka; Paolo Radice; Paolo Peterlongo; the EPICOLON Consortium

doi:10.1371/journal.pone.0085538

Loading metrics

Open Access

Peer-reviewed

Research Article

Association between CASP8 –652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study

Barbara Pardini ,

* E-mail: barbara.pardini@hugef-torino.org

Affiliation Genomic Variation in Human Populations and Complex Diseases Unit, Human Genetics Foundation, Turin, Italy
⨯
Paolo Verderio,

Affiliation Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Sara Pizzamiglio,

Affiliation Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Carmela Nici,

Affiliation Fondazione Istituto Italian Foundation for Cancer Research di Oncologia Molecolare, Milan, Italy
⨯
Maria Valeria Maiorana,

Affiliation Fondazione Istituto Italian Foundation for Cancer Research di Oncologia Molecolare, Milan, Italy
⨯
Alessio Naccarati,

Affiliations Molecular and Genetic Epidemiology Unit, Human Genetics Foundation, Turin, Italy, Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Ludmila Vodickova,

Affiliations Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic, First Medical Faculty, Charles University, Prague, Czech Republic
⨯
Veronika Vymetalkova,

Affiliations Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic, First Medical Faculty, Charles University, Prague, Czech Republic
⨯
Silvia Veneroni,

Affiliation Department of Experimental Oncology and Molecular Medicine, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Maria Grazia Daidone,

Affiliation Department of Experimental Oncology and Molecular Medicine, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Fernando Ravagnani,

Affiliation Immunohematology and Transfusion Medicine Service, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Tiziana Bianchi,

Affiliation Associazione Italiana Volontari Sangue Comunale Milano, Milan, Italy
⨯
Luis Bujanda,

Affiliation Gastroenterology Department, Hospital Donostia, Networked Biomedical Research Centre for Hepatic and Digestive Diseases, Basque Country University, San Sebastián, Spain
⨯
Angel Carracedo,

Affiliation Galician Public Foundation of Genomic Medicine, Centro de Investigación Biomédica en Red de Enfermedades Raras, Genomics Medicine Group, Hospital Clínico, Santiago de Compostela, University of Santiago de Compostela, Galicia, Spain
⨯
Antoni Castells,

Affiliation Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
⨯
Clara Ruiz-Ponte,

Affiliation Galician Public Foundation of Genomic Medicine, Centro de Investigación Biomédica en Red de Enfermedades Raras, Genomics Medicine Group, Hospital Clínico, Santiago de Compostela, University of Santiago de Compostela, Galicia, Spain
⨯
Hans Morreau,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Kimberley Howarth,

Affiliation Molecular and Population Genetics Laboratory and National Institute for Health Research Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Angela Jones,

Affiliation Molecular and Population Genetics Laboratory and National Institute for Health Research Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Sergi Castellví-Bel,

Affiliation Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
⨯
Li Li,

Affiliation Department of Family Medicine and Community Health and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Ian Tomlinson,

Affiliation Molecular and Population Genetics Laboratory and National Institute for Health Research Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Tom Van Wezel,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Pavel Vodicka,

Affiliations Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic, First Medical Faculty, Charles University, Prague, Czech Republic
⨯
Paolo Radice,

Affiliation Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Paolo Peterlongo,

Affiliation Fondazione Istituto Italian Foundation for Cancer Research di Oncologia Molecolare, Milan, Italy
⨯
[ ... ],
the EPICOLON Consortium

¶Members of the EPICOLON Consortium can be found in the acknowledgments.
⨯
[ view all ]
[ view less ]

Association between CASP8 –652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study

Barbara Pardini,
Paolo Verderio,
Sara Pizzamiglio,
Carmela Nici,
Maria Valeria Maiorana,
Alessio Naccarati,
Ludmila Vodickova,
Veronika Vymetalkova,
Silvia Veneroni,
Maria Grazia Daidone

Published: January 21, 2014
https://doi.org/10.1371/journal.pone.0085538

Reader Comments

Post a new comment on this article

Correction required

Posted by BarbaraPardini on 27 Jan 2014 at 08:36 GMT

The authors infom that in the present version of the paper there are some mistakes that will be corrected as soon as possible.
In particular:
1) The correct authors order is "Barbara Pardini, Paolo Verderio, Sara Pizzamiglio, Carmela Nici, Maria Valeria Maiorana, Alessio Naccarati, Ludmila Vodickova, Veronika Vymetalkova, Silvia Veneroni, Maria Grazia Daidone, Fernando Ravagnani, Tiziana Bianchi, EPICOLON Consortium, Luis Bujanda, Angel Carracedo, Antoni Castells, Clara Ruiz-Ponte, Hans Morreau, Kimberley Howarth, Angela Jones, Sergi Castellví-Bel, Li Li, Ian Tomlinson, Tom Van Wezel, Pavel Vodicka, Paolo Radice, Paolo Peterlongo"

2) The correct Institute affiliation for Drs Carmela Nici, Maria Valeria Maiorana and Paolo Peterlongo is " IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy"

3) Table 2 presents some problems in the format: all decimal numbers should be with dots but in the resulting pdf the table presents a mix of dots and commas.

We are sorry for these problems and we hope to fix these problems as soon as possible.
Best regards,

Barbara Pardini
HuGeF - Human Genetics Foundation - Torino
Genomic variation in human population and complex diseases
Via Nizza, 52 - 10126 Torino (Italy)

Tel. +39 011 670 9543
Fax +39 011 670 9546
barbara.pardini@hugef-torino.org
www.hugef-torino.org

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Hereditary nonpolyposis colorectal cancer
Is the Subject Area "Hereditary nonpolyposis colorectal cancer" applicable to this article?

Thanks for your feedback.
Consortia
Is the Subject Area "Consortia" applicable to this article?

Thanks for your feedback.
Ethnic epidemiology
Is the Subject Area "Ethnic epidemiology" applicable to this article?

Thanks for your feedback.
Genetic epidemiology
Is the Subject Area "Genetic epidemiology" applicable to this article?

Thanks for your feedback.
Genetic predisposition
Is the Subject Area "Genetic predisposition" applicable to this article?

Thanks for your feedback.
Italian people
Is the Subject Area "Italian people" applicable to this article?

Thanks for your feedback.

Association between CASP8 –652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study

Association between CASP8 –652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Correction required

Posted by BarbaraPardini on 27 Jan 2014 at 08:36 GMT