About the Authors

Kaoru Ohashi

Contributed equally to this work with: Kaoru Ohashi, Hisako Komada

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Hisako Komada

Contributed equally to this work with: Kaoru Ohashi, Hisako Komada

Affiliation Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo-ku, Kobe, Japan

Shinsuke Uda

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Hiroyuki Kubota

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Toshinao Iwaki

Affiliation Department of Computational Biology, Graduate School of Frontier Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Hiroki Fukuzawa

Affiliation Faculty of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yasunori Komori

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Masashi Fujii

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yu Toyoshima

Affiliation Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Kazuhiko Sakaguchi

Affiliation Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo-ku, Kobe, Japan

Wataru Ogawa

ogawa@med.kobe-u.ac.jp (WO); skuroda@bs.s.u-tokyo.ac.jp (SK)

Affiliation Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo-ku, Kobe, Japan

Shinya Kuroda

ogawa@med.kobe-u.ac.jp (WO); skuroda@bs.s.u-tokyo.ac.jp (SK)

Affiliations Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo, Japan, Department of Computational Biology, Graduate School of Frontier Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KO SU H. WO H. Kubota SK. Performed the experiments: H. Komada KS WO. Analyzed the data: KO SU HF. Contributed reagents/materials/analysis tools: KO SU TI YK MF YT. Wrote the paper: KO WO SK.