In Vivo Near-Infrared Fluorescence Imaging of Apoptosis Using Histone H1-Targeting Peptide Probe after Anti-Cancer Treatment with Cisplatin and Cetuximab for Early Decision on Tumor Response

Hyun-Kyung Jung; Kai Wang; Min Kyu Jung; In-San Kim; Byung-Heon Lee

doi:10.1371/journal.pone.0100341

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Open Access

Peer-reviewed

Research Article

In Vivo Near-Infrared Fluorescence Imaging of Apoptosis Using Histone H1-Targeting Peptide Probe after Anti-Cancer Treatment with Cisplatin and Cetuximab for Early Decision on Tumor Response

Hyun-Kyung Jung,

Affiliations Department of Biochemistry and Cell Biology and School of Medicine, Kyungpook National University, Daegu, Korea, BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Science, Graduate School, Kyungpook National University, Daegu, Korea
⨯
Kai Wang,

Affiliation Department of Plastic Surgery, Henan Provincial People's Hospital, Zhengzhou, Henan, China
⨯
Min Kyu Jung,

Affiliation Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
⨯
In-San Kim,

Affiliations Department of Biochemistry and Cell Biology and School of Medicine, Kyungpook National University, Daegu, Korea, BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Science, Graduate School, Kyungpook National University, Daegu, Korea
⨯
Byung-Heon Lee

* E-mail: leebh@knu.ac.kr

Affiliations Department of Biochemistry and Cell Biology and School of Medicine, Kyungpook National University, Daegu, Korea, BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Science, Graduate School, Kyungpook National University, Daegu, Korea
⨯

In Vivo Near-Infrared Fluorescence Imaging of Apoptosis Using Histone H1-Targeting Peptide Probe after Anti-Cancer Treatment with Cisplatin and Cetuximab for Early Decision on Tumor Response

Hyun-Kyung Jung,
Kai Wang,
Min Kyu Jung,
In-San Kim,
Byung-Heon Lee

Published: June 20, 2014
https://doi.org/10.1371/journal.pone.0100341

About the Authors

Hyun-Kyung Jung

Affiliations Department of Biochemistry and Cell Biology and School of Medicine, Kyungpook National University, Daegu, Korea, BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Science, Graduate School, Kyungpook National University, Daegu, Korea

Kai Wang

Affiliation Department of Plastic Surgery, Henan Provincial People's Hospital, Zhengzhou, Henan, China

Min Kyu Jung

Affiliation Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea

In-San Kim

Byung-Heon Lee

* E-mail: leebh@knu.ac.kr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ISK BHL. Performed the experiments: HKJ. Analyzed the data: HKJ BHL. Contributed reagents/materials/analysis tools: KW MKJ. Contributed to the writing of the manuscript: HKJ BHL.

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Cancer treatment
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Apoptosis
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Cancers and neoplasms
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Gastric cancer
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Fluorescence imaging
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Breast cancer
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In vivo imaging
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Stomach
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