About the Authors

Carsten Jers

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Malwina Michalak

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Dorte M. Larsen

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Kasper P. Kepp

Affiliation Department of Chemistry, Technical University of Denmark, Lyngby, Denmark

Haiying Li

Affiliation Department of Biochemistry and Molecular Biology, Southern University of Denmark, Odense, Denmark

Yao Guo

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Finn Kirpekar

Affiliation Department of Biochemistry and Molecular Biology, Southern University of Denmark, Odense, Denmark

Anne S. Meyer

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Jørn D. Mikkelsen

jdm@kt.dtu.dk

Affiliation Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark

Competing Interests

The authors have filed a patent application (“A mutant sialidase having trans-sialidase activity for use in production of sialylated glycans”, European Patent Application No. 13163551.8). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in our guide for authors. All material relating to the patent is available in connection with this submission and the present article was used as the framework to design the patent application.

Author Contributions

Conceived and designed the experiments: CJ MM JDM KPK. Performed the experiments: CJ MM DML HL YG. Analyzed the data: CJ MM ASM JDM. Contributed reagents/materials/analysis tools: JDM ASM FK. Wrote the paper: CJ MM.