About the Authors

Claudia H. T. Tam

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Janice S. K. Ho

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Ying Wang

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Vincent K. L. Lam

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Heung Man Lee

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Guozhi Jiang

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Eric S. H. Lau

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Alice P. S. Kong

Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Xiaodan Fan

Affiliation Department of Statistics, The Chinese University of Hong Kong, Hong Kong SAR, China

Jean L. F. Woo

Affiliation Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Stephen K. W. Tsui

Affiliation School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Maggie C. Y. Ng

Affiliation Center for Genomics and Personalized Medicine Research, Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America

Wing Yee So

Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Juliana C. N. Chan

Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Ronald C. W. Ma

rcwma@cuhk.edu

Affiliations Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China, Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SKWT MCYN WYS JCNC RCWM. Performed the experiments: VKL. Analyzed the data: CHTT JSKH YW HML GJ ESHL XF. Contributed reagents/materials/analysis tools: APSK SKWT MCYN WYS JCNC RCWM. Wrote the paper: CHTT JCNC RCWM. Recruitment of patients: APSK JLFW YW MCYN WYS JCNC RCWM.